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Study On The Refining Process Of Betaine
Dec 12, 2017

The chemical name of betaine is 2- (N, N, N-trimethyl) aminoacetic acid inner salt, English name: Betaine, molecular formula C5H11NO2, relative molecular weight 117.15. Pure betaine white needle crystal, soluble in water and methanol, the solubility of 100 g water 160 g, 100 g methanol solubility of 55 g, slightly soluble in ethanol.
Betaine is a quaternary alkaloid, an efficient methyl donor that modulates the osmotic pressure in animals and promotes fat metabolism and protein synthesis. Betaine is widespread in animals and plants and plays an important role in the metabolism of organisms. Betaine is used for a wide range of purposes, can be used as feed additives in the pharmaceutical industry as an efficient supplier of methyl and for the production of pharmaceutical bio-fermentation VB12. In addition, betaine as a non-ionic surfactant is also widely used in Japan, printing and dyeing and other industries. The product has good prospects for development and broad market prospects.
There are currently two methods for preparing betaine. One is adding calcium chloride from beet molasses, filtering the filtrate, adding hydrochloric acid into the filtrate, and concentrating and crystallizing to obtain the finished product; the other is chemical synthesis, chloroacetic acid, trimethylamine and hydrogen After the reaction of sodium oxide concentration, purification, crystallization obtained betaine.
However, the first method produces betaine hydrochloride; the second method produces a product that contains large amounts of sodium chloride. The taste of the products produced by these two methods are not high, the products can only be used as feed additives and other industries. In the pharmaceutical industry as an efficient supplier of methyl and biomedical fermentation for the production of such as betaine betaine and other requirements of high purity, the betaine can not be applied in the pharmaceutical industry. On the basis of chemical synthesis, the authors studied the new technology of betaine refining, that is, the purity of betaine was up to 99.5% by using cation exchange resin method to synthesize betaine. The value of betaine to further improve.