Trimethylglycine (TMG) is also known as glycine betaine, but the name trimethylglycine means three methyl groups attached to each glycine molecule.Back to 1950s,people found that trimethylglycine is good for heart health.TMG works in a similar way to vitamin B12,which provides additional methyl groups to speed up the conversion of homocysteine back to methionine as methyl donnor.When the trimethyglycine group provides a homocysteine molecule,it is converted to the non-toxic amino acid methionine.The studies show that TMG can maintain the healthy homocysteine levels when TMG is alone or combined with other nutrients,proving to be an important nutrient for cardiovascular health.For example, in recent cross-cross studies, subjects taking > 360 mg/day of TMG had an average of 10% lower homocysteine concentrations and 19% lower C-reactive protein concentrations than subjects taking < 260 mg/day of TMG.  

Betaine can protect heart by reducing the blood homocysteine, is a metabolite of methionine which cann’t be synthesized in the body.Hyperhomocysteine is an independent risk factor for cardiovascular problems.Betaine can promote the conversion of homocysteine to methionine,effectively reduce the concentration of homocysteine in blood,to achieve the effect of heart protection.

Betaine protects the liver from alcohol damage: lipid peroxidation, steatosis and fibrosis.Improve liver cells, reduce the transaminase, improve steatosis and necrotizing problems.Reduce the blood fat content and the excessive formation of liver fat.