Lettuce, a water-sensitive leafy vegetable, often faces yield and quality loss under drought stress. Glycine betaine, known for its osmoprotective properties, is being explored as a foliar treatment to help maintain leaf turgor and metabolic function during water-limited periods.

Applied at early vegetative stages, glycine betaine may help stabilize cell membranes and reduce transpiration-induced damage. Studies have shown that it supports chlorophyll content, enhances photosynthetic activity, and can contribute to more uniform leaf expansion—even under moderate drought conditions.

This natural compound does not replace irrigation but can serve as a stress-mitigation tool, particularly in regions prone to inconsistent rainfall. Frequent low-dose foliar spraying seems to provide more promising results, especially when combined with other good agricultural practices.

For producers focused on both yield and appearance, incorporating glycine betaine into lettuce management programs can be a worthwhile addition under stress-prone growing conditions.