According to epidemiological surveys, 9% to 42% of people under 50 years of age have mild homocysteine, and these people are likely to have thromboembolism, myocardial ischemia, peripheral artery occlusion or cerebral artery occlusion and other cardiovascular and cerebrovascular diseases. The prevalence is very high among the affected population, especially women.

Homocysteine is caused by a lack of methyl-supplying nutrients in food (mainly betaine, also known as lycium barbarine), which prevents water from leaking out of cells and keeps them normal in size and function.Provide the body with sufficient methyl),the methionine circulation in the body is blocked, homocysteine can not be converted into methionine and accumulate in the blood.  Increasing the intake of foods rich in betaine will alleviate many of the conditions associated with homocysteine and reduce the risk of cardiovascular disease in healthy individuals.  

Expert points out, the body of choline can be converted into betaine, but choline is the main raw material for the synthesis of acetylcholine and phospholipids, is a necessary component to maintain normal brain nutrition, usually only a small amount of choline translate into betaine, so the demand of betaine relies mainly on the diet, and betaine safe dose for 9 to 15 grams per day.