In animal agriculture, creatine supplementation has been explored for its potential to improve growth performance and meat quality. Studies have shown that dietary supplementation with creatine monohydrate (CMH) and guanidinoacetic acid (GAA) can enhance muscle development and alter creatine metabolism in finishing pigs. This supplementation increased concentrations of creatine and phosphocreatine in muscle tissues and influenced gene expression related to creatine metabolism.

These findings suggest that creatine supplementation could be a valuable strategy in livestock production to improve meat quality and growth performance. However,it's important to consider species-specific responses and dosing strategies. Further research is necessary to establish standardized guidelines for creatine use in various animal production systems.